United States · Social Security disability · Blue Book

SSA listing 12.04: depressive and bipolar disorders.

The adult Blue Book listing, quoted as printed and explained in plain terms.

Listing 12.04 is met by paragraph A plus paragraph B, or paragraph A plus paragraph C. Paragraph A asks for medical documentation of either five or more listed depressive symptoms or three or more listed bipolar symptoms; B asks for extreme limitation of one, or marked limitation of two, of four areas of mental functioning; C is the "serious and persistent" route.

Source: 20 CFR 404, Subpart P, Appendix 1 (eCFR)Retrieved November 2, 2026Text as of October 29, 2026

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The short version

Listing 12.04 is met by paragraph A plus paragraph B, or paragraph A plus paragraph C. Paragraph A asks for medical documentation of either five or more listed depressive symptoms or three or more listed bipolar symptoms; B asks for extreme limitation of one, or marked limitation of two, of four areas of mental functioning; C is the "serious and persistent" route.

The text below is the adult listing from 20 CFR Part 404, Subpart P, Appendix 1 as published on the eCFR, current through October 29, 2026 and read on November 2, 2026. Children are evaluated under the 112.xx series; this page covers only the adult listing.

Listing 12.04 as printed

Listing 12.04, as printed (adult listing)

12.04 Depressive, bipolar and related disorders (see 12.00B3), satisfied by A and B, or A and C:

A. Medical documentation of the requirements of paragraph 1 or 2:

1. Depressive disorder, characterized by five or more of the following: a. Depressed mood; b. Diminished interest in almost all activities; c. Appetite disturbance with change in weight; d. Sleep disturbance; e. Observable psychomotor agitation or retardation; f. Decreased energy; g. Feelings of guilt or worthlessness; h. Difficulty concentrating or thinking; or i. Thoughts of death or suicide.

2. Bipolar disorder, characterized by three or more of the following: a. Pressured speech; b. Flight of ideas; c. Inflated self-esteem; d. Decreased need for sleep; e. Distractibility; f. Involvement in activities that have a high probability of painful consequences that are not recognized; or g. Increase in goal-directed activity or psychomotor agitation.

AND B. Extreme limitation of one, or marked limitation of two, of the following areas of mental functioning (see 12.00F): 1. Understand, remember, or apply information (see 12.00E1). 2. Interact with others (see 12.00E2). 3. Concentrate, persist, or maintain pace (see 12.00E3). 4. Adapt or manage oneself (see 12.00E4).

OR C. Your mental disorder in this listing category is "serious and persistent;" that is, you have a medically documented history of the existence of the disorder over a period of at least 2 years, and there is evidence of both:

1. Medical treatment, mental health therapy, psychosocial support(s), or a highly structured setting(s) that is ongoing and that diminishes the symptoms and signs of your mental disorder (see 12.00G2b); and

2. Marginal adjustment, that is, you have minimal capacity to adapt to changes in your environment or to demands that are not already part of your daily life (see 12.00G2c).

How listing 12.04 is built

Listing 12.04 is one of five mental-disorder listings that have three paragraphs. Section 12.00A2 of the introductory text says your disorder "must satisfy the requirements of both paragraphs A and B, or the requirements of both paragraphs A and C." Paragraph A is the medical part: it must be present in your medical evidence. Paragraph B is the functional part. Paragraph C is an alternative to B for disorders the regulation calls "serious and persistent."

So there are two doors through the same first paragraph. Everything turns on A first, because neither B nor C can be satisfied without it. That is why the regulation puts A first and spends the introductory text explaining what kind of evidence counts.

Paragraph A in plain terms

The two sub-paragraphs of A are counted lists, and the counts are different on purpose. A depressive disorder needs five or more of nine listed symptoms; a bipolar disorder needs three or more of seven. The words "characterized by" and the lettered items mean the listing is describing a documented clinical picture, not asking for a particular diagnosis label. Section 12.00B3b separately names the kinds of diagnoses SSA evaluates here, which include bipolar disorders (I or II), cyclothymic disorder, major depressive disorder and persistent depressive disorder.

Notice that "Observable psychomotor agitation or retardation" is the one depressive item that depends on someone observing it; the others can come from reported symptoms. Section 12.00C lists the evidence SSA looks at, including reported symptoms, mental status examinations, rating scales, the type and effect of medication and therapy, and observations of how you function during examinations or therapy.

What the regulation says this category covers (12.00B3)

12.00B3, quoted

These disorders are characterized by an irritable, depressed, elevated, or expansive mood, or by a loss of interest or pleasure in all or almost all activities, causing a clinically significant decline in functioning. Symptoms and signs may include, but are not limited to, feelings of hopelessness or guilt, suicidal ideation, a clinically significant change in body weight or appetite, sleep disturbances, an increase or decrease in energy, psychomotor abnormalities, disturbed concentration, pressured speech, grandiosity, reduced impulse control, sadness, euphoria, and social withdrawal.

Examples of disorders that we evaluate in this category include bipolar disorders (I or II), cyclothymic disorder, major depressive disorder, persistent depressive disorder (dysthymia), and bipolar or depressive disorder due to another medical condition.

TNAADO's reading: the category description and the examples tell you which kinds of conditions are assessed here. They are not extra criteria. The criteria are the paragraphs of the listing itself.

Paragraph B: the four areas and the five-point scale

Paragraph B is a functional test. SSA rates the effect of the disorder on four areas of mental functioning on a five-point scale (12.00F2) and the listing is satisfied by extreme limitation of one, or marked limitation of two.

Paragraph B areaWhat 12.00E says it refers to (quoted)
Understand, remember, or apply information (12.00E1)This area of mental functioning refers to the abilities to learn, recall, and use information to perform work activities.
Interact with others (12.00E2)This area of mental functioning refers to the abilities to relate to and work with supervisors, co-workers, and the public.
Concentrate, persist, or maintain pace (12.00E3)This area of mental functioning refers to the abilities to focus attention on work activities and stay on task at a sustained rate.
Adapt or manage oneself (12.00E4)This area of mental functioning refers to the abilities to regulate emotions, control behavior, and maintain well-being in a work setting.
Point on the scaleDefinition (12.00F2, quoted)
NoneYou are able to function in this area independently, appropriately, effectively, and on a sustained basis.
MildYour functioning in this area independently, appropriately, effectively, and on a sustained basis is slightly limited.
ModerateYour functioning in this area independently, appropriately, effectively, and on a sustained basis is fair.
MarkedYour functioning in this area independently, appropriately, effectively, and on a sustained basis is seriously limited.
ExtremeYou are not able to function in this area independently, appropriately, effectively, and on a sustained basis.

Paragraph B does not ask how severe the diagnosis is. It asks how far the disorder limits four work-related areas. Section 12.00F1 says SSA considers "the kind, degree, and frequency of difficulty you would have; whether you could function without extra help, structure, or supervision; and whether you would require special conditions."

For mood disorders, section 12.00F4 matters because moods cycle. It says SSA considers "how often you have exacerbations and remissions, how long they last, what causes your mental disorder to worsen or improve," and whether the area can be used "on a regular and continuing basis (8 hours a day, 5 days a week, or an equivalent work schedule)." It also says SSA will not find that you can work "solely because you have a period(s) of improvement (remission), or that you are disabled solely because you have a period of worsening (exacerbation)."

Paragraph C: "serious and persistent"

Paragraph C exists because treatment can quiet the obvious symptoms without making a person able to cope with change. Section 12.00G1 says "we recognize that mental health interventions may control the more obvious symptoms and signs of your mental disorder." C needs a medically documented history of at least two years and both C1 (ongoing treatment, therapy, supports or a highly structured setting that diminishes symptoms) and C2 (only marginal adjustment).

Section 12.00G2b adds that SSA looks at whether treatment happens "with a frequency consistent with accepted medical practice," and that if inconsistent treatment or non-compliance "is a feature of your mental disorder" and led to worsening, SSA will not use it as evidence that you did not receive ongoing treatment.

Reading 12.04 next to its neighbours

12.04 sits between 12.03 (schizophrenia spectrum and other psychotic disorders) and 12.05 (intellectual disorder). Trauma-related conditions such as PTSD are evaluated under 12.15 and anxiety and obsessive-compulsive disorders under 12.06, not here. Section 12.00B sets out which disorders SSA evaluates in each category, and several categories exclude their neighbours by name, so the category description is the place to check where a condition belongs.

What this page does not do

It does not diagnose, say which listing applies to you, estimate an outcome or advise on a claim. A listing is only one step: Social Security also decides disability through other steps and considers evidence this page does not reproduce. The regulation text changes over time; check the linked eCFR page for the current version.

Frequently asked questions

How many symptoms does paragraph A of listing 12.04 require?

Five or more of nine listed symptoms for a depressive disorder, or three or more of seven listed symptoms for a bipolar disorder, with medical documentation.

Does meeting paragraph A mean you meet listing 12.04?

No. The listing is satisfied by A and B, or A and C. Paragraph A alone is not enough.

What is the paragraph B standard?

Extreme limitation of one, or marked limitation of two, of four areas of mental functioning: understanding, remembering or applying information; interacting with others; concentrating, persisting or maintaining pace; and adapting or managing oneself.

What does "serious and persistent" mean in paragraph C?

A medically documented history of the disorder over at least two years, plus ongoing treatment or supports that diminish symptoms, and only marginal adjustment to change.

Does a period of improvement count against a claim under 12.04?

The regulation says SSA will not find that you can work solely because of a period of remission, or that you are disabled solely because of a period of worsening.

Does this page tell me whether I meet listing 12.04?

No. It reproduces the published criteria. Social Security decides disability, and this page is not medical or claim advice.

Sources

Read directly from the primary sources below on November 2, 2026 (eCFR text current through October 29, 2026). Quotations are the regulation text as printed; anything labelled as a reading is TNAADO's. The listings are amended and re-extended from time to time, so confirm the current text on the linked pages.

Reference, not an SSA determination, medical advice or claim advice

Listing criteria quoted from 20 CFR Part 404, Subpart P, Appendix 1 as of October 29, 2026 (eCFR). This page reproduces published criteria so you can read them; it does not diagnose, tell you whether you meet a listing, estimate an outcome or advise on a claim. Social Security decides disability using the full process in its regulations, including provisions this page does not reproduce. It is not legal, financial or medical advice; a benefits attorney, accredited representative or your clinician can review your situation.

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